Lytic Distal Femur Lesion (GCT)

Good case of an uncommon solitary lytic bone lesion.


This has the 4 hallmarks elaborated in Brandt and Helms:

  1. occurs only with a closed growth plate
  2. abuts articular surface: 84-99% come within 1 cm of the articular surface 1
  3. well defined with non-sclerotic margin (though < 5% may show some sclerosis 8)
  4. eccentric


As with most bone tumors, this is not a slam dunk as there are always mimics ranging from fibrous dysplasia to metastatic disease.



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